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proteintech 12212 1 ap  (Proteintech)


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    Structured Review

    Proteintech proteintech 12212 1 ap
    Proteintech 12212 1 Ap, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 31 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/proteintech+12212+1+ap/SSBP1+Antibody/pm40921294-204-19-19
    Average 93 stars, based on 31 article reviews
    proteintech 12212 1 ap - by Bioz Stars, 2026-09
    93/100 stars

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    Article Title: Phosphomimetic experiments do not support a causal role for TFAM phosphorylation in mtDNA elimination in sperm.
    Article Snippet: In sexually reproducing eukaryotes—particularly mammals—mitochondrial DNA (mtDNA) is typically inherited from a single parent, making uniparental mtDNA inheritance a fundamental feature of eukaryotic biology.. Recently, it has been suggested that spermatozoa contain no mtDNA because the matrix targeting sequence (MTS) of the mitochondrial transcription factor A (TFAM) becomes phosphorylated, which prevents the mitochondrial import of this protein essential for mtDNA replication.. In this study, we used a combination of the GeneSwap technique and phosphomimetic mutations to investigate the impact of TFAM MTS phosphorylation on mtDNA maintenance in cultured cells.



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